Primary Sclerosing Cholangitis

Primary sclerosing cholangitis (PSC) is a condition that affects the bile ducts. These ducts carry bile from the liver, where bile is produced, to the gallbladder, where it is stored, and to the small intestine, where it aids in digestion. Primary sclerosing cholangitis occurs because of inflammation in the bile ducts (cholangitis) that leads to scarring (sclerosis) and narrowing of the ducts. As a result, bile cannot be released to the gallbladder and small intestine, and it builds up in the liver.

Indiana University School of Medicine is actively conducting clinical research to advance the prevention, diagnosis, and treatment of liver, gastrointestinal, and pancreatic conditions. Patients, caregivers, and community members who are interested in learning more about current, open research studies are encouraged to explore our clinical studies database.

Participation in research is voluntary and may offer opportunities to contribute to medical advancements that improve patient care now and in the future.