Skip to main content
Indiana University School of Medicine
Indiana University School of Medicine
Department of Medicine
Other GI Motility and Neurogastroenterology Research Studies being conducted at IU School of Medicine.

Other GI Motility and Neurogastroenterology Research Studies

Investigators

23390-Saito, Akira

Akira Saito, MD

Assistant Professor of Clinical Medicine

Read Bio

5144-Wo, John

John M. Wo, MD

Douglas Rex Professor of Gastroenterology and Hepatology

Read Bio

Open Research Studies for Other Motility Research

Indiana University GI Neuromuscular Pathology Prospective Registry

Enrolling: Yes

Principle Investigator: John M. Wo, MD

Duration: 2 years

Primary Outcomes Measured: 

  1. Follow up clinical data will be obtained before, 6 months, 1.5 years, and 2 years after the full thickness biopsy
  2. Follow up data PAGI_SYM Overall Treatment Effect by Patient Overall Treatment Effect by Physician

Secondary Outcomes Measured:

  1. Responders will be defined as >50% improvement of the GCSI total score at 6 month after surgical GES.
  2. Patients with gastroparesis from type 1 DM versus patients with idiopathic gastroparesis.
  3. Patients with gastroparesis from type 1 DM versus gastroparesis from type 2 DM.
  4. Neuromuscular pathology results of the gastric body and proximal jejunum will be correlated with the following: Symptom severity (GCSI total score), predominant symptom presentation, severity of delayed gastric emptying.

Interested in this study? Please contact the coordinator below:
Maureen Schilling
maschi@iu.edu

View the study on clinicaltrials.gov

GI Motility Diagnosis Registry

Enrolling: Yes

Principle Investigator: John M. Wo, MD

Duration: TBD

Primary Outcomes Measured:  Identification of patients by accurate motility diagnosis.

Secondary Outcomes Measured:

  1. To develop Patient Reported Outcome (PRO) measurements in patients with small intestinal bacterial overgrowth (SIBO)
  2. To develop Patient Reported Outcome (PRO) measurements in patients with gastroparesis

Interested in this study? Please contact the coordinator below:
Maureen Schilling
maschi@iu.edu

Effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Plasma Insulin Levels

Enrolling: Yes

Principle Investigator: Thomas Nowak, MD

Duration: 1 visit.

Primary Outcome Measured:

  1. The purpose of this study is to evaluate whether electrically stimulating the nerve around the external ear will also stimulate the internal vagus nerve and influence the levels of substances in your body related to insulin production.

Interested in this study? Please contact the coordinator below:
Maureen Schilling
maschi@iu.edu

View the study on clinicaltrials.gov

Closed Research Studies for Other Motility Research

Enrolling: No

Principle Investigator: Akira Saito, MD

Duration: Recruiting 50 patients based in the US.

Primary Outcomes Measured:

  1. Develop a de novo CIPO-specific PRO that is able to capture change in core CIPO visible signs and symptoms across all etiologies and severity levels.
  2. Develop a de novo CIPO-specific PRO that is fit-for-purpose for use as a primary endpoint in a clinical trial setting.