The discipline of clinical pharmacology deals with the study of medications in humans and their effective, safe and economic use in patients. It bridges the gap between science and the practice of medicine through innovative research, development and regulation of medications. Since 1986, the Division of Clinical Pharmacology in the Department of Medicine at Indiana University School of Medicine remains at the forefront of advancing the science of clinical pharmacology, translational medicine and therapeutics for the benefit of patients.
Faculty
Faculty clinical pharmacologists within the Department of Medicine conduct basic, translational and clinical research designed to improve understanding and predicting therapeutic drug responses.
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Research
The division is focused on genetic and non-genetic mechanisms of inter-individual variability in drug effects. Broad research efforts encompass cardiology, nephrology, obstetrics, reproductive endocrinology, hematology/ oncology, GI/hepatology and infectious disease.
Education
The Division of Clinical Pharmacology offers a variety of postdoctoral fellowship programs, providing high quality training and research opportunities in the drug discovery and development process. In addition, our faculty mentor graduate students from within the Indiana University School of Medicine and Purdue University College of Pharmacy.
The Division of clinical pharmacology
Drug Interaction Database
The Flockhart Table™ is a cytochrome P450 drug-interaction reference tool focused on the human cytochrome P450 system. The information presented in this drug-interaction table is intended as general health information and as an educational tool. It is not intended as medical advice. Only a physician, pharmacist or other health care professional should advise a patient on medical issues and should do so using a medical history and other factors identified and documented as part of the health professional/patient relationship.
Indiana Institute for Personalized Medicine
The Indiana Institute for Personalized Medicine is improving the practice of medicine by advancing the personalization of therapy for a wide range of conditions — that is, finding the best drug for each patient. Scientists at the Institute for Personalized Medicine apply cutting-edge clinical, laboratory and informatics expertise to better understand why medicines work for individual patients, design new means of targeting therapies, and encourage the development of new therapies that benefit patients of all ages, genders and ethnicities.
Clinical Care
The ultimate goal of faculty clinical pharmacologists at IU School of Medicine is to personalize drug therapy by optimizing beneficial effects, while minimizing adverse effects and cost. The Division of Clinical Pharmacology and the Indiana Institute for Personalized Medicine are leading the implementation of genomically guided therapeutic dosing and selection through the school's clinical partnership with Indiana University Health.
Pharmacometrics Modeling and Simulation
The Indiana CTSI Pharmacometrics Modeling and Simulation Program (formerly the Disease and Therapeutic Response Modeling Program) supports quantitative pharmacology research from early drug development to clinical care in a variety of therapeutic areas. The mission of the program, to provide training regarding the application of pharmacometrics to enable development of personalized medicines, is achieved through provision of foundational learning, as well as participation in collaborative research which fosters active learning and real-world problem solving.