Indiana University School of Medicine leads a comprehensive program in Alzheimer's disease research spanning basic, translational and clinical research, focused on optimizing clinical care for patients with Alzheimer's disease. The school, ranked No. 6 in the nation for National Institute of Aging research, received $87 million in National Institutes of Health grants to fund Alzheimer's disease research. From developing the next generation of animal models and testing potential therapeutics to working alongside clinical research participants and patients in the state's largest health system, IU School of Medicine has a rich research program and expertise widely recognized around the world.
Basic and Preclinical Science
Basic scientists research the neurobiology and molecular genetics of Alzheimer’s disease to define disease mechanisms using animal models, identify therapeutic targets, rigorously test drugs and create molecules for potential drugs.
Clinical and Translational Science
Researchers in clinical and translational science test new methods to diagnose, treat and prevent Alzheimer’s disease, and advancing this research into improved diagnosis and care for patients living with the disease.
Clinical Innovation
Researchers in clinical and translational science test new methods to diagnose, treat and prevent Alzheimer’s disease, and advancing this research into improved diagnosis and care for patients living with the disease.
Featured News
Candice Brown joined the IU School of Medicine to grow the school’s neurovascular basic science and clinical research programs.
August 14, 2025
From folding proteins to unfolding memories: An AI journey through Alzheimer's
This is the final column in a four-part series from Taeho Jo, assistant professor of radiology and imaging sciences at the IU School of Medicine, titled "AI in Medicine: From Nobel Discoveries to Clinical Frontiers."August 01, 2025
New national center at IU to develop stem cell brain models to better understand Alzheimer’s disease
Indiana University is leading the way nationally as the home to one of only two centers in the United States dedicated to developing stem-cell-based models of the human brain to better understand the underlying causes of Alzheimer's disease and dementias.
July 31, 2025
IU School of Medicine researchers receive top awards at international Alzheimer’s disease conference
Research leaders at the IU School of Medicine will receive two of the top six awards given out by the Alzheimer’s Association at its annual international conference.July 28, 2025
Researchers bring promising Alzheimer’s drug target closer to potential clinical trials
IU School of Medicine researchers aim to develop a new treatment for neurodegeneration by targeting an immune cell-specific gene associated with Alzheimer's disease.
July 14, 2025
IU-led Alzheimer’s drug discovery center moves forward with promising new therapeutic targets
IU School of Medicine researchers have identified a portfolio of novel drug targets that may accelerate promising treatments for people living with Alzheimer’s disease.
July 14, 2025
AI in Medicine: What is your 'aha' moment?
This column is the third in a four-part series from Taeho Jo, titled "AI in Medicine: From Nobel Discoveries to Clinical Frontiers."
July 11, 2025
The Protein Folding Problem: The day AI unlocked a secret of life
This column is the second in a four-part series from Taeho Jo, titled "AI in Medicine: From Nobel Discoveries to Clinical Frontiers."
June 20, 2025
Timothy Richardson is a research professor of medicine at the IU School of Medicine and helps lead the TREAT-AD drug discovery center.
June 16, 2025