
Raj Vuppalanchi, MB,BS
Professor of Medicine
Director of Hepatology
Associate Program Director
Bio
Dr. Raj Vuppalanchi is a tenured Professor of Medicine and Director of Hepatology at Indiana University School of Medicine. He joined the Division of Gastroenterology and Hepatology in 2007 after completing fellowships in Clinical Pharmacology and Gastroenterology & Hepatology at Indiana University. An experienced hepatologist, he provides comprehensive care for patients with a wide range of liver disorders at the Digestive and Liver Disorders Clinic at Indiana University Hospital.
Dr. Vuppalanchi's research focuses on patient-centered approaches to advancing therapies for metabolic dysfunction-associated steatohepatitis (MASH), cholestatic and autoimmune liver diseases, including primary sclerosing cholangitis (PSC), primary biliary cholangitis (PBC), and autoimmune hepatitis (AIH), as well as cirrhosis. He has made significant contributions to the development and application of non-invasive methods for assessing liver disease severity, including transient elastography for liver and spleen stiffness measurement.
In addition, his research has advanced understanding of the hepatic safety of pharmaceuticals, herbal products, and dietary supplements. Dr. Vuppalanchi serves as a principal investigator for numerous industry-sponsored and NIH-funded multicenter clinical trials, including studies conducted through the MASH Clinical Research Network (MASH CRN) and the Drug-Induced Liver Injury Network (DILIN). He also serves as principal investigator for the Indiana Clinical and Translational Sciences Institute (CTSI) Phase I clinical trials program, with a particular focus on hepatic impairment studies.
Through his clinical, research, and leadership efforts, Dr. Vuppalanchi continues to advance the understanding and treatment of liver disease while expanding therapeutic options for patients.
| Year | Degree | Institution |
|---|---|---|
| 2007 | Fellowship | IU School of Medicine, Indianapolis, IN |
| 2005 | Fellowship | IU School of Medicine, Indianapolis, IN |
| 2003 | Residency | Long Island College Hospital, Brooklyn, NY |
| 1998 | MB,BS | Gandhi Medical College |
- Metabolic dysfunction-associated steatohepatitis (MASH)
- Drug-induced liver injury (DILI)
- Pathogenesis and treatment of liver disease
- Alterations in drug metabolism following gastric bypass surgery
- Altered drug metabolism in patients with cirrhosis
- Muscle cramps in patients with cirrhosis
Eadon MT; Rosenman MB; Zhang P; Fulton CR; Callaghan JT; Holmes AM; Levy KD; Gupta SK; Haas DM; Vuppalanchi R; Benson EA; Kreutz RP; Tillman EM; Shugg T; Pierson RC; Gufford BT; Pratt VM; Zang Y; Desta Z; Dexter PR; Skaar TC; The pharmacogenomics journal 2023 Sep 9
Sanyal AJ; Shankar SS; Yates KP; Bolognese J; Daly E; Dehn CA; Neuschwander-Tetri B; Kowdley K; Vuppalanchi R; Behling C; Tonascia J; Samir A; Sirlin C; Sherlock SP; Fowler K; Heymann H; Kamphaus TN; Loomba R; Calle RA; Nature medicine 2023 Sep 7
Murillo Perez CF; Ioannou S; Hassanally I; Trivedi PJ; Corpechot C; van der Meer AJ; Lammers WJ; Battezzati PM; Lindor KD; Nevens F; Kowdley KV; Bruns T; Cazzagon N; Floreani A; Mason AL; Gulamhusein A; Ponsioen CY; Carbone M; Lleo A; Mayo MJ; Dalekos GN; Gatselis NK; Thorburn D; Verhelst X; Parés A; Londoño MC; Janssen HLA; Invernizzi P; Vuppalanchi R; Hirschfield GM; Hansen BE; Levy C; Global PBC Study Group; Liver international : official journal of the International Association for the Study of the Liver 2023 May 8
Noureddin M; Mena E; Vuppalanchi R; Samala N; Wong M; Pacheco F; Polanco P; Sakkal C; Antaramian A; Chang D; Noureddin N; Kohli A; Harrison SA; Gawrieh S; Alkhouri N; Truong E; Hepatology communications 2023 May 4
Chalasani N; Vuppalanchi R; Lammert C; Gawrieh S; Braun JV; Zhuang J; Ibarra A; Ross DA; Nerenberg M; Quake SR; Sninsky JJ; Toden S; Hepatology communications 2023 May 23
Sarkis Y; Saleem N; Vuppalanchi R; Gromski M; Hepatic medicine : evidence and research 2023 Mar 28
Vuppalanchi R; Are V; Telford A; Young L; Mouchti S; Ferreira C; Kettler C; Gromski M; Akisik F; Chalasani N; JHEP reports : innovation in hepatology 2023 Jun 29
Culver A; Hamang M; Wang Y; Jiang H; Yanum J; White E; Gawrieh S; Vuppalanchi RK; Chalasani NP; Dai G; Yaden BC; Biomedicines 2023 Jul 6
Vilar-Gomez E; Vuppalanchi R; Gawrieh S; Samala N; Chalasani N; Hepatology (Baltimore, Md.) 2023 Jan 3
Vilar-Gomez E; Vuppalanchi R; Gawrieh S; Pike F; Samala N; Chalasani N; The American journal of gastroenterology 2023 Feb 16
Orman ES; Desai AP; Ghabril MS; Nephew LD; Patidar KR; Holden J; Samala NR; Gawrieh S; Vuppalanchi R; Sozio M; Lacerda M; Vilar-Gomez E; Lammert C; Liangpunsakul S; Crabb D; Masuoka H; Dakhoul L; Pan M; Gao S; Chalasani N; The American journal of gastroenterology 2023 Aug 7
Kowdley KV; Bowlus CL; Levy C; Mayo MJ; Pratt DS; Vuppalanchi R; Younossi ZM; The American journal of gastroenterology 2022 Sep 21
Halegoua-DeMarzio D; Navarro V; Ahmad J; Avula B; Barnhart H; Barritt AS; Bonkovsky HL; Fontana RJ; Ghabril MS; Hoofnagle JH; Khan IA; Kleiner DE; Phillips E; Stolz A; Vuppalanchi R; The American journal of medicine 2022 Oct 14
Wong VW; Tak WY; Goh GBB; Cheng PN; Lawitz EJ; Younossi ZM; Vuppalanchi R; Younes Z; Alkhouri N; Wang L; Liu J; Kersey K; Myers RP; Harrison SA; Goodman Z; Trauner M; Romero-Gomez M; Anstee QM; Nguyen MH; Okanoue T; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2022 Jan 22
Vuppalanchi R; Karpen SJ; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2022 Dec 11
Vilar-Gomez E; Vuppalanchi R; Mladenovic A; Samala N; Gawrieh S; Newsome PN; Chalasani N; Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2021 Dec 25
S-Are V; Yoder L; Samala N; Nephew L; Lammert C; Vuppalanchi R; Annals of hepatology 2020 Sep 12
- Management of cirrhosis
- Metabolic dysfunction-associated steatotic liver disease (MASLD)
- Chronic viral hepatitis (hepatitis B and C)
- Primary biliary cholangitis (PBC)
- Primary sclerosing cholangitis (PSC)
- Alcohol-associated liver disease
- Drug-induced liver injury (DILI)
Desc: Trustees' Teaching Award
Scope: University
Date: 2017-05-01