Cancers that arise in musculoskeletal tissue, non-musculoskeletal cancers and anti-cancer therapies can damage both bone and muscle. The Cancer Research team focuses on cancers arising from musculoskeletal cells (sarcomas), the interactions between cancer and bone in the metastatic niche, and the effects of cancer and cancer therapies on the musculoskeletal system. These investigators also study how the musculoskeletal system can influence cancer risk, development, progression and outcomes.
Who We Are
Our mission is to improve outcomes for individuals with cancers that affect the musculoskeletal system by studying how tumors and cancer therapies impact bone and muscle health. We aim to develop innovative strategies that preserve strength, mobility and quality of life throughout the cancer journey.
We envision a future where every patient benefits from personalized treatments that protect bone and muscle, reduce long-term complications and support full recovery.
In 2024, team members authored 35 total publications. Nine of these were in journals with an impact factor of 10 or above.
Cancer Research team members have held prestigious leadership roles and received nationally recognized awards, including:
- President of ASBMR
- Fellow of the ASBMR
- Fellow of the ORS
- Stephen M. Krane Award
- Louis V. Avioli Founders Award
Team Leaders
Indiana University School of Medicine Faculty Investigators
Thomas M. O'Connell, PhD
Associate Professor of Otolaryngology-Head & Neck Surgery
Harikrishna Nakshatri, PhD
Marian J. Morrison Professor of Breast Cancer Research
Lilian I. Plotkin, PhD
Assistant Dean for Faculty Affairs and Professional Development
Attaya Suvannasankha, MD
Harry and Edith Gladstein Professor of Cancer Research
