MAGNETOM Prisma 3T MRI
A research-dedicated Siemens MAGNETOM Prisma 3T 60cm bore whole body scanner was installed in August 2014. This system facilitates the delivery of high anatomical detail to expand imaging capabilities. Key features include: Zero helium boil-off technology, gradient strength up to 80 mT/m at slew rate up to 200 T/m/s, up to 50 cm FOV; RF system with 64 receive channels supporting up to 204 coil elements; Magnet homogeneity at 40 cm DSV – 0.25 ppm; multiple RF coils including the newly FDA approved 64-channel Head and Neck coil, a 20-channel Head and Neck Coil as well as an array of other anatomy coils (neck, cardiac, shoulder, knee, etc.); Tim 4G +Dot, Tim TX True Shape, Syngo D13 software with InLine Automated Processing, Auto Align slice positioning, Phoenix image reproducibility, Intelligent Coil Control auto coil position detection, full suite of imaging techniques, including multi-nuclear, advanced cardiac, Syngo advanced neuroimaging applications. IDEA and ICE development environment and analysis packages are also available.
Siemens Vision 600 PET/CT
A research-dedicated Siemens Biograph Vision 600 PET/CT system was installed at the IU Health Neuroscience Center in July 2020. This system was the first system worldwide to integrate a TwinBeam Dual Energy (TBDE) CT scanner with positron emission tomography. The PET component consists of 8 detector rings with 38 detector blocks per ring. Each detector block consists of a 4x2 arrangement of mini blocks (5x5 array of 3.2x3.2x20mm crystals coupled to a SiPM array (16x16mm with 16 output channels). The PET system has 25.6 cm axial field-of-view and a 78-cm bore. Intrinsic spatial resolution for the system is approximately 3.5mm FWHM near the center of the field-of-view with a sensitivity of 16.4 kcps/MBq based on NEMA NU-2 conformance standards. Time-of-flight resolution is less than 210ps for all detector combinations. The TBDE CT system enables simultaneous acquisition of high and low kV images in a single scan by splitting the X-ray beam with two filters. Twin beam spectral CT enables better soft tissue delineation and expanded capabilities for attenuation correction. PET features include: dynamic listmode data acquisition capabilities; multiple filter selections and algorithms for reconstruction, including OSEM and FBP; FlowMotion technology for continuous bed motion data acquisition. CT features include: 128-slice CT with STRATON X-ray tube with 0.3s CT rotation speed, Adaptive Dose shielding and CARE Dose4D, z-Sharp technology for 0.33mm isotropic resolution, iMAR metal artifact reduction, and Adaptive 4D Spiral technology for full-coverage perfusion studies.
Bruker BioSpec 94/30 MR Scanner with gradient inserts, 1H MRI CryoProbeTM, and PET Insert Si 20/12
This multimodality imaging system is located within a dedicated imaging facility which has been integrated with a preclinical laboratory care facility. This system became operational in February 2020. Key features include: true simultaneous PET-MR data acquisition, zero helium boil-off technology, 9.4T superconducting magnet system, actively shielded gradients, built-in 300 mT/m gradient amplitude, 1040 T/m/s maximum slew rate, multiple pre-clinical brain/body/surface/volume coils, MR compatible physiologic monitoring system, body temperature control system, Autopac motorized sample support system and multiple application packages. The system includes additional gradient inserts for high-resolution imaging. The B-GA12S HP w/ RF Coil gradient shim insert for optimal performance for small sample sizes. The 12S gradient coil insert has 660 mT/m peak strength with 4570 T/m/s maximum slew rate for high resolution diffusion imaging. The Resonance Research Inc. (RRI) gradient insert coil is designed for ex vivo only super-resolution MRI with a maximum gradient strength of 2500 mT/m and 25000 T/m/s slew rate. The CryoProbeTM is a cryogenically cooled MRI coil (20-30 degrees K) to decrease electronic noise for 2- to 5-fold increase in signal-to-noise ratio (SNR) imaging of mice. The PET insert is a 3-ring PET system that can be inserted into the bore of the magnet for simultaneous PET/MR imaging or can be operated independently as a standalone system. The PET system is based upon Si PET detector technology. Both the MR and PET systems are operated using the Bruker ParaVision 360 Acquisition Workplace software version. Contact Erin Jarvis for more information.
