Stark Neurosciences Research Institute

Bringing together the scientific community in a dynamic, collaborative organization that advances discovery of neuroscience-related disease mechanisms and therapeutic strategies and disseminates and applies this knowledge to prevent, treat and cure disease.

a picture of the Stark Neurosciences building

Mission and Vision

Stark Neurosciences Research Institute, under the leadership of Executive Director Bruce T. Lamb, PhD, is dedicated to improving outcomes for persons suffering from disorders of the nervous system. For more than 20 years, Stark Neurosciences Research Institute has provided a collaborative space on the Indiana University School of Medicine campus in downtown Indianapolis where scientists and clinician-scientists from different disciplines across Indiana University can work together on translational science to investigate devastating disorders, ultimately seeking novel therapeutics to treat patients alongside partnering physicians. Researchers at the prestigious institute have made groundbreaking discoveries in Alzheimer's disease, psychiatric disorders, traumatic brain injury and much else.

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Transformational neuroscience research

Stark Neurosciences Research Institute is at the cutting edge for the role the IU School of Medicine plays locally and globally to shape new treatments for devastating disorders of the nervous system, including Alzheimer’s disease and related dementias, as well as addiction, glaucoma, spinal cord and brain injuries, chronic pain and psychiatric disorders.

a researcher works in a lab

Exponential growth in research funding

Stark Neuroscience Research Institute investigators at IU School of Medicine received $89 million in National Institute of Health grant funding in 2024, a 300% increase since 2016. Alzheimer's disease and other neurodegenerative disorders related grants comprise a large majority of the funding.

Research at Stark Neurosciences Research Institute is not only reflected across departments at IU School of Medicine and at other IU campuses statewide but at several universities and institutions, such as Purdue University, the Jackson Laboratory, University of Pittsburgh and Sage Bionetworks.

Research Interests

FEATURED NEWS

a researcher uses a pipette

Study finds genetic risk factor for Alzheimer’s disease disrupts brain connectivity

A well-known genetic risk factor for Alzheimer’s disease worsens damage to white matter tissues in the brain that are crucial for communication between different brain regions.

December 16, 2025

students present research at a symposium

Stark Neurosciences Research Institute launches new Alzheimer’s disease summer research program for undergraduate students

The new IU School of Medicine program is geared toward training the next generation of scientists investigating Alzheimer’s disease and related dementias.

November 21, 2025

Researchers view brain scans

Researchers develop tool to track progression of Alzheimer’s, dementias based on metabolic, vascular brain changes

The findings highlight the major role inflammation plays in neurodegenerative disease progression.

November 07, 2025

Upcoming Events

Jan 06 12:00pm

Membership Seminar: Speaker & Yehui Zhu, PhD

Stark Seminar Series: Spring 2026

NEUROSCIENCES RESEARCH BUILDING

Jan 15 12:00pm

Stark Seminar Series: Natasha O’Brown, PhD

Stark Seminar Series: Spring 2026

NEUROSCIENCES RESEARCH BUILDING

Jan 22 12:00pm

Stark Seminar Series: Laila Alibiglou, PT, PhD

Stark Seminar Series: Spring 2026

NEUROSCIENCES RESEARCH BUILDING

American Brain Coalition

American Brain Coalition LogoStark Neurosciences Research Institute is proud to be a member of the American Brain Coalition, a nonprofit umbrella organization of nearly 200 leading professional neurological, psychological and psychiatric associations and patient organizations, along with clinicians, researchers, academia, industry and government agencies in the United States. The coalition's goal is to increase awareness and understanding and to advocate for increased research and resources — to improve a person's quality of life and enhance a national commitment toward cures for patients with brain disorders. Stark is one of 10 academic institutions in the country dedicated to advancing brain research as members of the American Brain Coalition.