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Center for Diabetes and Metabolic Diseases

The Islet and Physiology Core provides specialized services and expertise to scientists at the P30-funded Center for Diabetes and Metabolic Diseases.

Islet and Physiology Core

The Islet and Physiology Core has dedicated 1,389 square feet of space to address the needs of researchers requiring islet isolation, islet functional and morphometric characterization, and rodent physiology characterization services.

Services

The following are the most routinely requested services. Core directors are available to provide consultation to optimize the design and interpretation of results from the Islet and Physiology Core.

Blood Glucose Measurement
EchoMRI
Glucose Tolerance Test
In Vivo GSIS
Insulin Tolerance Test
Metabolic Cage Analysis
Serial Blood Sampling
Streptozotocin Injections

Beta or Alpha Cell Mass Analysis
CODEX Multiplex Imaging
Live Pancreatic Slice Generation
Slide Scan - Brightfield
Slide Scan - Fluorescence
Tissue Immunohistochemistry
Tissue Collection

Cytosolic Calcium Measurement
Exosome Quantification and Size Analysis
Islet Respiration
Islet Perifusion
Mouse Islet Isolation
Rat Islet Isolation
Viral Transduction of Rodent or Human Islets and Generation of Pseudoislets

Abdominal Imaging Window Placement
Human Islet Transplant into Mouse Kidney Surgery
Mouse Islet Transplant into Mouse Kidney Surgery

Contact the Core

To request research support from this core facility, email the team.

Core Leadership and Personnel

5100-Evans-Molina, Carmella

Carmella Evans-Molina, MD, PhD

Director, Indiana Diabetes Research Center

43265-Spaeth, Jason

Jason M. Spaeth, PhD

Assistant Professor of Pediatrics

Jacqueline Aquino

Jacqueline Aquino

Kara Orr

Kara Orr

Lata Udari

Lata Udari