Angelia D. Lockett, PhD
Assistant Professor of Medicine
Key Publications
Year | Degree | Institution |
---|---|---|
2008 | PhD | Indiana University |
2001 | BS | Jackson State University |
Dr. Lockett is currently an Assistant Professor in the Department of Medicine, Division of Pulmonary, Critical Care, Sleep and Occupational Medicine at IUSOM where she is mentored by Dr. Roberto Machado, MD and Dr. Micheala Aldred, PhD. Her research interests are to investigate the etiology of the vascular abnormalities that mediate pulmonary arterial hypertension (PAH), and to identify molecules or pathways to target for therapeutic intervention. She is specifically interested in identifying the role of maladaptive mitochondrial function which may alter metabolic pathways to promote the pathogenesis of PAH, and whether differences in mitochondrial gene expression and function exists in minority PAH patients which leads to higher mortality.
Chen J; Lockett A; Zhao S; Huang LS; Wang Y; Wu W; Tang M; Haider S; Velez Rendon D; Khan R; Liu B; Felesena N; Sysol JR; Valdez-Jasso D; Tang H; Bai Y; Natarajan V; Machado RF; International journal of molecular sciences 2022 Nov 22
Gomes MT; Bai Y; Potje SR; Zhang L; Lockett AD; Machado RF; International journal of molecular sciences 2022 Feb 22
Bai Y; Lockett AD; Gomes MT; Stearman RS; Machado RF; Cell biochemistry and biophysics 2021 Jun 16
Desc: K01 - Regulation of UPRmt activation in the development of pulmonary vascular remodeling in PAH
Scope: National
Date: 2022-08-01