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A Multicenter, Open-Label, Randomized, Bupivacaine-Controlled Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Aged 0 to Less Than 6 ...
This Phase 1, multicenter, open-label, randomized, bupivacaine-controlled study is designed to evaluate the pharmacokinetics (PK) and safety of EXPAREL vs. bupivacaine HCl for postsurgical analgesia in pediatric subjects aged 0 ...
Cleopattra: Effects of Nnc6019-0001 Versus Placebo on Cardiovascular Outcomes in Participants with Transthyretin Amyloid Cardiomyopathy
This study will find out if a new medicine called NNC6019-0001 can help reduce the risk of heart-related death and illness in participants with a condition called transthyretin amyloid cardiomyopathy ...
Alnylam ALN-APP-001: Phase I, Placebo-Controlled Trial of ALN-APP in Participants with Early-Onset Alzheimer’S Disease
Who is Eligible Ages 18+ Must have had symptoms of Alzheimer’s disease prior to age 65 Diagnosis of Alzheimer’s disease Must be able to complete MRI Must be able to tolerate lumbar puncture No history of ...
Sc2i-Woundx-001-Woundx Pilot Trial: Proof of Concept Feasibility for the Clinical Operations of Woundx in Aiding Clinicians Identify Wounds That Are Ready for Surgical Closure
The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital. The WounDx device is experimental and ...
A Phase 2, Two-Stage, Randomized, Double-Blind, Placebo-Controlled, Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Rls-0071 in Newborns with Moderate ...
Hypoxic-ischemic encephalopathy (HIE) affects approximately 4,000 to 12,000 persons annually in the United States. Mortality from HIE has been reported up to 60%, with at least 25% of survivors left ...
Efficacy and Safety of Nnc0487-0111 Compared to Placebo on Morbidity and Mortality in People with Heart Failure with Preserved or Mildly Reduced Ejection Fraction ...
This study is being done to look at the safety and effect of NNC0487-0111 in people with Heart Failure with preserved Ejection Fraction (HFpEF) or Heart Failure with mildly reduced ...
An Observational, Long-Term Safety Study of Tzield® in Patients with Stage 2 Type 1 Diabetes
The purpose of this research is to collect general information on patients with stage 2 type 1 diabetes (T1D) and further information on the long-term effects of TZIELD® in patients ...
Rezpegaldesleukin in New Onset Type 1 Diabetes Mellitus
This Phase 2 study is a 2-arm, multi-center, double-masked, placebo-controlled, 2:1 randomized sequential trial design in new onset T1D participants (within 100 days of diagnosis). THIS STUDY IS ENROLLING BY INVITATION ...
Inhale-1St: Technosphere Insulin (Afrezza) in Combination with Basal Insulin for Youth with Newly-Diagnosed Type 1 Diabetes
INHALE-1st is a Phase 2, single-arm, multi-center, clinical study evaluating the safety and efficacy of Afrezza in combination with subcutaneously-injected basal insulin (BI) for youth 10 to THIS STUDY IS ...
FORAGER-1: a Phase 1, Open-Label, Multicenter Study of LOXO-435 (LY3866288) in Locally Advanced or Metastatic Solid Tumors Including Urothelial Cancer with FGFR3 Alterations
This is an open-label, multi-center, phase 1a/b study in participants with FGFR3-altered advanced solid tumors, including metastatic urothelial cancer (UC). The main purpose of this study is to learn more ...