Jae W. Lee, MD, PhD

Key Publications

Cancer Immunobiology:

Cho Y*, Lee JW*, Shin SM, Hernandez AG, Yuan X, Schneider J, Hooper JE, Wood LD, Jaffee EM, Deshpande A, Ho WJ. Computational Modeling of Cellular Influence Delineates Functionally Relevant and Distinct Cellular Neighborhoods in Primary and Metastatic Pancreatic Ductal Adenocarcinoma. Cancer Immunol Res. 2026 Apr 2;14(4):571-584. PubMed PMID: 41592755. (*)Co-first authors.

Stone ML, Lee J, Lee JW, Coho H, Tariveranmoshabad M, Wattenberg MM, Choi H, Herrera VM, Xue Y, Choi-Bose S, Zingone SK, Patel D, Markowitz K, Delman D, Balachandran VP, Beatty GL. Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins. Nat Immunol. 2024 May;25(5):755-763. PubMed PMID: 38641718.

Lee JW, Stone ML, Porrett PM, Thomas SK, Komar CA, Li JH, Delman D, Graham K, Gladney WL, Hua X, Black TA, Chien AL, Majmundar KS, Thompson JC, Yee SS, O'Hara MH, Aggarwal C, Xin D, Shaked A, Gao M, Liu D, Borad MJ, Ramanathan RK, Carpenter EL, Ji A, de Beer MC, de Beer FC, Webb NR, Beatty GL. Hepatocytes direct the formation of a pro-metastatic niche in the liver. Nature. 2019 Mar;567(7747):249-252. PubMed PMID: 30842658.

Cancer genetics and biomarkers:

Wang Y, Lih TM, Lee JW, Ohtsuka T, Hozaka Y, Mino-Kenudson M, Adsay NV, Luchini C, Scarpa A, Maker AV, Kim GE, Paulino J, Chen L, Woo J, Jiao L, Sun Z, Goodman D, Pflüger MJ, Roberts NJ, Matthaei H, Goggins MG, Wood LD, Furukawa T, Zhang H, Hruban RH. Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct patterns and potential markers of progression. Cancer Cell. 2025 Nov 10;43(11):2156-2170.e6. PubMed PMID: 40882635.

Lee JW, Hruban RH, Brosens LAA, Condello V, Nikiforova MN, Singhi AD, Pancreatic Cyst Alliance. RNA Sequencing Identifies Frequent Mitogen-activated Protein Kinase-associated Fusion Genes in Intraductal Tubulopapillary Neoplasms of the Pancreas. Gastroenterology. 2023 Jun;164(7):1310-1313.e6. PubMed PMID: 36801389.

Lee JW, Zhang Y, Yoshizawa T, Argani P, Wood LD, Oshima K. Cancerization of ducts in hilar cholangiocarcinoma. Virchows Arch. 2022 Aug;481(2):1-10. PubMed PMID: 35527321.

Complete list of publications can be found below:

• PubMed
• ORCID
• Google Scholar