
Yann Gibert, PhD
Professor of Medical & Molecular Genetics
- Address
-
IB 447
MMGE
IN
Indianapolis, IN
Bio
Dr. Yann Gibert has over 25 years of experience in using the zebrafish as a vertebrate model in 4 countries (Germany, France, USA, and Australia) on three continents. Throughout his career, Dr. Gibert reviewed R01 grants equivalent for the National Health Medical Research Council (NHMRC, Australia); Association Nationale pour la Recherche (ANR, France); The Fund for Scientific Research (FNRS, Belgium) and NSF type grants: Australia Research Council (ARC, Australia); Diabetes Australia Research Trust (DART) and the Schrödinger Foundation (Austria). Dr. Gibert also managed several funded projects in Europe, Australia and recently in the US (NIH).
He serves as a mentor for undergraduate and graduate researchers a swell as post-doctoral research fellows and MS resident and fellows, he is an active member of the International Zebrafish Society (IZS) and the Zebrafish Disease Model Society (ZDMS) and has delivered numerous presentations and published over 65 journal articles.
Key Publications
Nguyen KUC., Cox CK., Stephenson D., D’Alessandro A., Mendoza LD., Taylor EB., Monroe JD. and Gibert Y. (2025). Resolution of Inflammation Increases Hematopoietic Stem Cell Number and Erythropoiesis. In Press Blood Red Cells and Iron
Jackman WR., Lynch VJ. and Gibert Y. (2025). Challenging and redefining Dollo's law of evolution: re-appearance of lost structures. BMC Ecol Evol 24:62.
Tomalka JA., Owings A., Ziegler CG., Robinson TO., Wichman TG., Laird H., Williams HB., Ghaliwal NS., Shalek AK., Horwitz BH., Ordovas-Montanes J., Glover SC. and Gibert Y. (2025). Eicosanoids and of pro-resolving mediators’ synthesis is increased in SARS-CoV-2 infection in severe COVID-19. FASEB J 39(9):e70600.
McLaurin D., Tucker S., Siddique S., Challagundla L., Gibert Y. and Hebert M. (2025). A novel role for coilin in vertebrate innate immunity. FASEB J 39(8):e70580.
Herrera M., Vianello S., Mitchell L., Chamot Z., Lorin-Nebel C., Roux N., Besseau L., Gibert Y. and Laudet V. (2025). From Genes to Pathways: A Curated Gene Approach to Accurate Pathway Reconstruction in Teleost Fish Transcriptomics. J Exp Zool B DOI: 10.1002/jez.b.23299
Pu S., Bushnaq H., Munro C., Gibert Y., Sharma R., Mishra V. and Dumée LF. (2024). Perspectives on transportation pathways of microplastics across the MENA region. NPJ Clean Water 7 :114
Begum S., Irwin SD., Cox CK., Huang Z., Wilson JJ., Monroe JD. and Gibert Y. (2024). Anti-ovarian cancer migration and toxicity characteristics of a platinum(IV) pro-drug with axial HDAC inhibitor ligands in zebrafish models. Investigational New Drugs doi: 10.1007/s10637-024-01479-3
Konadu B., Cox CK. and Gibert Y. (2024). Microinjection of Free Fatty Acid and Triacylglycerol in zebrafish embryos. STAR Protocols 24:5(2):103086
Jackman WR., Miranda Portillo LS., Cox CK., Ambrosio A. and Gibert Y. (2024). Blocking endogenous retinoic acid degradation induces oral tooth formation in zebrafish. PNAS 121(11)e2321162121
Konadu B., Hosler JP., Gibert Y.* and Edwards KS. (2023). Analysis of oxygen consumption rates in zebrafish reveals differences based on sex, age and physical activity recovery. Front. Physiol. 13, 14:127366 * Corresponding author
Logan MK., Irvin SD., Enfrin M., Arafat H., Dumée LF. and Gibert Y. (2023). Textile nanofibers exposure induces inflammatory response, apoptosis and alters zebrafish vascular development during embryogenesis. J Environ. Chem. Eng. 11:110727.
Konadu B., Cox CK., Garreett MR. and Gibert Y. (2023). Excess glucose or fat differentially affects gene expression and appetite regulation during zebrafish embryogenesis. iScience 26(7):107063.
Roux N., Minura S., Dussene M., Tara Y., Lee F., de Bernard S., Reynaud M., Salis P., Barua A., Boulahtouf A., Balaguer P., Gauthier K., Lecchini D., Gibert Y., Besseau L. and Laudet V. (2023). The multi-Level regulation of clownfish metamorphosis by thyroid hormones. Cell Reports 42(7):112661.
Gopal U., Monroe JD., Marudamuthu AS., Begum S., Walters BJ., Stewart RA., Washington CW., Gibert Y.* and Zachariah MA. (2023). Development of a Triple Negative Breast Cancer Leptomeningeal Disease Model in Zebrafish. Cells 12(7), 995 https://doi.org/10.3390/cells12070995. * Corresponding author
Shrestha AP., RSaravanakumarawat A., Konadu B., Madireddy S., Gibert Y. and Vaithianathan T. (2022). Embryonnic hyperglycemia delays the development of retinal synapses in a zebrafish model. IJMS. 23(17):9693 doi: 10.3390/ijms23179693
Kaur H., Rawat D., Poria P., Sharma U., Gibert Y., Dumée LF., Sharma RS. and Mishra V. (2022). Ecotoxic effects of microplastics and contaminated microplastics - Emerging evidence and perspective. STOTEN 841: 156593. doi: 10.1016/j.scitotenv.2022.15659
Tanzin T., Perera K., Gibert Y., Ward AC. and Liongue C. (2022). Cytokine receptor-like factor 3 (CRLF3) contributes to early zebrafish hematopoiesis. Front Immunol. 13:910428 doi: 10.3389/fimmu.2022.910428
Monroe JD and Gibert Y. (2022). A novel circular RNA acts as a key modulator of epidermal growth factor receptor signaling in non-small cell lung cancer. ExRNA 4:11. doi: 10.21037/exrna-22-7.
Monroe JD., Fraher D., Huang X., Mellett NA., Meikle PJ., Sinclair AJ., Lirette ST., Maihle NJ., Gong Z. and Gibert Y. (2022). Identification of novel lipid biomarkers in xmrk- and Myc-induced models of hepatocellular carcinoma in zebrafish Cancer & Metabolism. 10(1):7. doi: 10.1186/s40170-022-00283-y
Lee J., Gibert Y. and Dumée L. (2021). Nano and micro plastics in water processing. Where are we at? J water Proc Eng 43:102281.
Monroe JD., Basheer F. and Gibert Y. (2021). Xmrks the Spot: Fish Models for Investigating Epidermal Growth Factor Receptor Signaling in Cancer Research. Cells 10(5):1132.
Gibert Y.* and Chung BC. (2021). Fish as a model for endocrine systems. Mol Cell Endocrinol 8:111316. doi: 10.1016/j.mce.2021.111316 *corresponding author
Monroe JD., Moolani SA., Irihamye EN., Lett KE., Hebert MD., Gibert Y.* and Smith ME. (2021). Cisplatin and phenanthriplatin modulate long-noncoding RNA expression in A549 and IMR90 cells revealing regulation of microRNAs, Wnt/β-catenin and TGF-β signaling. Scientific Reports 11(1): 10408 *corresponding author
Monroe JD., Moolani SA., Irihamye EN., Speed JS., Gibert Y.* and Smith ME. (2021). Comparative next generation sequencing analysis of cisplatin and the monofunctional platinum(II) complex, phenanthriplatin, in A549 non-small cell lung cancer and IMR90 lung fibroblast cell lines. Cells 8;9(12):2637. doi: 10.3390/cells9122637 *corresponding author
Fraher D, Mann RJ, Dubuisson MJ., Ellis MK, Tingsheng Y, Walder K, Ward AC, Winkler CW. and Gibert Y. (2021). Retinoic acid signaling and the endocannabinoid system combine to influence bone growth. Mol Cell Endocrinol 529:111267 doi: 10.1016/j.mce.2021.111267
Singh A, Enjapoori Gibert Y. and Dwyer K. (2020). The influence of bovine and human beta casomorphin 5 and 7 on pancreatic hormone regulation and beta cell regeneration. Biol Open 9(8):bio049304 doi: 10.1242/bio.049304
Schubert M and Gibert Y. (2020). Retinoids in Embryonic Development. Biomolecules. 10(9)1278. doi: 10.3390/biom10091278.
Jenkins H., Rivera-Gonzalez OJ., Gibert Y. and Speed JS. (2020). Endothelin-1 in the Pathophysiology of Obesity and Insulin Resistance. Obesity Reviews 21(12)e13086 doi: 10.1111/obr.13086
Gibert Y* and Maihle (2020). Agnostic Cancer Immunotherapy: Fact or Fiction? Ec Endocrinol Metab Res SI.02:01-02. * Corresponding author
Sadier A., Jackman WR., Laudet V. and Gibert Y. (2020). Vertebrate tooth row formation: is it signaled by a single organizing tooth? BioEssays e1900229. doi: 10.1002/bies.201900229
Enfrin M, Lee J, Gibert Y, Basheer F, Kong L. and Dumée L. (2020). Release of toxic nanoplastics due to microplastics fragmentation under low shear forces, an insidious threat. HAZMAT 384:121393.
Year | Degree | Institution |
---|---|---|
2007 | Postdoctoral Training | Institute of Functional Genomics of Lyon (IGFL) |
2004 | PhD | University of Konstanz |
2001 | M.Sc. | University of Limerick |
1997 | BSC | University of Pau |
Dr. Gilbert's research interests include developing zebrafish models of human diseases and cancers.