62070-Mustafa, Hiba

Hiba Mustafa, MD

Assistant Professor of Clinical Obstetrics & Gynecology

Director, Fetal Surgery

Director, Placenta Accreta Spectrum Program

Address
UH 2440
OBGY
IN
Indianapolis, IN

Bio

 

Dr. Hiba J. Mustafa currently serves as the Director of Fetal Surgery, the Director of the Placenta Accreta Spectrum Program, and the Director of Ultrasound Elective at Indiana University and Riley Children’s Hospital.

She is a distinguished Maternal-Fetal Medicine specialist with a subspecialty in Fetal Medicine and Surgery.

Dr. Mustafa practices at Fetal Center at Riley Children's and Indiana University Health where she plays a leading role in both the clinical and research aspects

Dr. Mustafa is a dedicated physician-scientist, boasting numerous publications in fetal diagnosis and therapy. She has garnered multiple research funds and currently serves as the principal investigator and co-investigator on several international collaborative research projects. Her clinical and research interests encompass medical and surgical therapy for complex fetal conditions, management of multiple gestations, and innovative ultrasound techniques, including first-trimester ultrasound, fetal echocardiography, fetal neurosonography, and 3D/4D imaging for diagnosing abnormal fetal and placental conditions.

Her contributions to the field reflect her commitment to improving outcomes for both mothers and their babies through cutting-edge research and clinical excellence.

Key Publications

Dr. Hiba Mustafa NCBI Link:

https://www.ncbi.nlm.nih.gov/myncbi/1TAJAjBiDAmM3a/bibliography/public/

 

Highlighted Publications:

Mustafa HJ, Sambatur EV, Shamshirsaz AA, Johnson S, Moise KJ Jr, Baschat AA, Verweij EJTJ, Javinani A, Kilby MD, Lopriore E, Rose R, Devlieger R, Snowise S, Sachs UJ, Khalil A.  Monitoring and Management of Hemolytic Disease of the Fetus and Newborn Based on an International Expert Delphi Consensus. Am J Obstet Gynecol. 2024 Nov 13;. doi: 10.1016/j.ajog.2024.11.003. [Epub ahead of print] PubMed PMID: 39547350.
 
Mustafa HJ, Khalil A, Johnson S, Gordijn SJ, Ganzevoort W, Melling C, Koh CJ, Mandy GT, Kilby MD, Johnson A, Quintero RA, Ryan G, Shamshirsaz AA, Nassr AA. Fetal lower urinary tract obstruction: international Delphi consensus on management and core outcome set. Ultrasound Obstet Gynecol. 2024 Nov;64(5):635-650. doi: 10.1002/uog.27684. PubMed PMID: 38748971.
 
Mustafa HJ, Sambatur EV, Pagani G, D'Antonio F, Maisonneuve E, Maurice P, Zwiers C, Verweij JEJT, Flood A, Shamshirsaz AA, Jouannic JM, Khalil A. Intravenous immunoglobulin for the treatment of severe maternal alloimmunization: individual patient data meta-analysis. Am J Obstet Gynecol. 2024 Oct;231(4):417-429.e21. doi: 10.1016/j.ajog.2024.03.044. Epub 2024 Apr 7. PubMed PMID: 38588966.
 
Bonanni G, Zargarzadeh N, Krispin E, Northam WT, Bevilacqua E, Mustafa HJ, Shamshirsaz AA. Prenatal Surgery for Open Fetal Spina Bifida in Patients with Obesity: A Review of Current Evidence and Future Directions. J Clin Med. 2024 Sep 24;13(19). doi: 10.3390/jcm13195661. Review. PubMed PMID: 39407721; PubMed Central PMCID: PMC11477046.
 
Mustafa HJ, Javinani A, Morning ML, D'Antonio F, Pagani G, Puranik PM, Khalil A, Shamshirsaz AA. Characteristics and Outcomes of Fetal Cardiac Rhabdomyoma With or Without mTOR Inhibitors, a Systematic Review and Meta-Analysis. Prenat Diagn. 2024 Aug 20;. doi: 10.1002/pd.6640. [Epub ahead of print] PubMed PMID: 39164800.
 
Mustafa HJ, Jawwad M, Iqbal Mansoor A, Pagani G, D'Antonio F, Khalil A. Right ventricular outflow tract obstruction in twin-to-twin transfusion syndrome undergoing laser surgery: A systematic review and meta-analysis. Acta Obstet Gynecol Scand. 2024 Aug;103(8):1513-1521. doi: 10.1111/aogs.14825. Epub 2024 Mar 14. PubMed PMID: 38482999; PubMed Central PMCID: PMC11266639.
 
Panunzi C, Cardinali F, Khalil A, Mustafa HJ, Spinillo A, Rizzo G, Flacco ME, Maruotti G, D'Antonio F. Ultrasound prediction of fetal macrosomia in pregnancies complicated by diabetes mellitus: a systematic review and meta-analysis. J Perinat Med. 2024 Jul 26;52(6):623-632. doi: 10.1515/jpm-2024-0121. Print 2024 Jul 26. PubMed PMID: 38860644.
 
Mustafa HJ, Aghajani F, Bairmani ZA, Khalil A. Transplacental non-steroidal anti-inflammatory drugs versus expectant management in fetal Ebstein anomaly with circular shunt: Systematic review and meta-analysis. Prenat Diagn. 2024 Jun;44(6-7):773-782. doi: 10.1002/pd.6446. Epub 2023 Oct 30. Review. PubMed PMID: 37902170.
 
Mustafa HJ, Aghajani F, Jawwad M, Shah N, Abuhamad A, Khalil A. Fetal cardiac intervention in hypoplastic left heart syndrome with intact or restrictive atrial septum, systematic review, and meta-analysis. Prenat Diagn. 2024 Jun;44(6-7):747-757. doi: 10.1002/pd.6420. Epub 2023 Aug 19. Review. PubMed PMID: 37596875.
 
Mustafa HJ, Kalafat E, Prasad S, Heydari MH, Nunge RN, Khalil A. Machine learning prediction of hypertension and diabetes in twin pregnancies using characteristics at prenatal care entry: a nationwide study. Ultrasound Obstet Gynecol.2024 May 28;. doi: 10.1002/uog.27710. [Epub ahead of print] PubMed PMID: 38805609.
 
Mustafa HJ, Aghajani F, Patrick E, Baerz MM, Arias-Sánchez P, Khalil A. Perinatal outcomes following fetoscopic laser surgery for early twin-to-twin transfusion syndrome: Systematic review and meta-analysis. Acta Obstet Gynecol Scand.2024 May;103(5):824-831. doi: 10.1111/aogs.14806. Epub 2024 Feb 28. Review. PubMed PMID: 38415823; PubMed Central PMCID: PMC11019523.
 
Javinani A, Qaderi S, Hessami K, Shainker SA, Shamshirsaz AA, Fox KA, Mustafa HJ, Subramaniam A, Khandelwal M, Sandlin AT, Duzyj CM, Lyell DJ, Zuckerwise LC, Newton JM, Kingdom JC, Harrison RK, Shrivastava VK, Greiner AL, Loftin R, Genc MR, Atasi LK, Abdel-Razeq SS, Bennett KA, Carusi DA, Einerson BD, Gilner JB, Carver AR, Silver RM, Shamshirsaz AA. Delivery outcomes in the subsequent pregnancy following the conservative management of placenta accreta spectrum disorder: a systematic review and meta-analysis. Am J Obstet Gynecol. 2024 May;230(5):485-492.e7. doi: 10.1016/j.ajog.2023.10.047. Epub 2023 Nov 2. Review. PubMed PMID: 37918506.
 
Mustafa HJ, Barbera JP, Sambatur EV, Pagani G, Yaron Y, Baptiste CD, Wapner RJ, Brewer CJ, Khalil A. Diagnostic yield of exome sequencing in prenatal agenesis of corpus callosum: systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2024 Mar;63(3):312-320. doi: 10.1002/uog.27440. Review. PubMed PMID: 37519216.
 
Mustafa HJ, Burns CT, Heydari MH, Javinani A, Bidulescu A, Habli M, Khalil A. Contribution of obesity to racial and ethnic disparities in the risk of fetal myelomeningocele: a population-based study. AJOG Glob Rep. 2024 Feb;4(1):100290. doi: 10.1016/j.xagr.2023.100290. eCollection 2024 Feb. PubMed PMID: 38274636; PubMed Central PMCID: PMC10808985.
 
Heydari MH, Sadeghian A, Khadivi G, Mustafa HJ, Javinani A, Nadjmi N, Khojasteh A. Prevalence, trend, and associated risk factors for cleft lip with/without cleft palate: a national study on live births from 2016 to 2021. BMC Oral Health. 2024 Jan 7;24(1):36. doi: 10.1186/s12903-023-03797-z. PubMed PMID: 38185687; PubMed Central PMCID: PMC10771673.
 
Mustafa HJ, Aghajani F, Verma D, Asghar M, Khalil A. Prenatal Risk Factors and Outcomes of Pseudoamniotic Band Sequence following Fetoscopic Laser Surgery: Systematic Review, and Meta-Analysis. Fetal Diagn Ther. 2024;51(1):66-75. doi: 10.1159/000534210. Epub 2023 Oct 25. PubMed PMID: 37879304.
 
Mustafa HJ, Javinani A, Muralidharan V, Khalil A. Diagnostic performance of 32 vs 36 weeks ultrasound in predicting late-onset fetal growth restriction and small-for-gestational-age neonates: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2024 Jan;6(1):101246. doi: 10.1016/j.ajogmf.2023.101246. Epub 2023 Dec 10. Review. PubMed PMID: 38072237.
 
Mustafa HJ, Javinani A, Heydari MH, Saldaña AV, Rohita DK, Khalil A. Selective intrauterine growth restriction without concomitant twin-to-twin transfusion syndrome, natural history, and risk factors for fetal death: A systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2023 Oct;5(10):101105. doi: 10.1016/j.ajogmf.2023.101105. Epub 2023 Jul 30. Review. PubMed PMID: 37527736.
 
Mustafa HJ, Sambatur EV, Barbera JP, Pagani G, Yaron Y, Baptiste CD, Wapner RJ, Khalil A. Diagnostic yield with exome sequencing in prenatal severe bilateral ventriculomegaly: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2023 Sep;5(9):101048. doi: 10.1016/j.ajogmf.2023.101048. Epub 2023 Jun 11. Review. PubMed PMID: 37311485.
 
Mustafa HJ, Arab K, Javinani A, Garg S, Nawab S, Habli M, Khalil A. Prenatal predictors of need for cerebrospinal fluid diversion in infants following prenatal repair of open spina bifida; systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2023 Aug;5(8):100983. doi: 10.1016/j.ajogmf.2023.100983. Epub 2023 Apr 24. Review. PubMed PMID: 37098391.
 
Rice SM, McLaren RA Jr, Mustafa HJ, Dugoff L, Al-Kouatly HB. Connecting the dots: Carrier screening and the Genetic Information Nondiscrimination Act in the United States. Prenat Diagn. 2023 Aug;43(9):1142-1149. doi: 10.1002/pd.6405. Epub 2023 Jul 12. PubMed PMID: 37392371.
 
Mustafa HJ, Javinani A, Seif K, Aghajani F, Makar EJ, Selhorst S, Crimmins S. Prepregnancy Roux-en-Y gastric bypass vs sleeve gastrectomy: a systematic review, pairwise, and network meta-analysis of obstetrical and neonatal outcomes.Am J Obstet Gynecol MFM. 2023 Jun;5(6):100914. doi: 10.1016/j.ajogmf.2023.100914. Epub 2023 Mar 7. Review. PubMed PMID: 36889438.
 
Krispin E, Mustafa HJ, Espinoza J, Nassr AA, Sanz Cortes M, Donepudi R, Harman C, Mostafaei S, Turan O, Belfort MA, Shamshirsaz AA. Prediction of dual survival following fetoscopic laser photocoagulation for twin-twin transfusion syndrome. Ultrasound Obstet Gynecol. 2023 Apr;61(4):511-517. doi: 10.1002/uog.26089. PubMed PMID: 36191157.
 
Krispin E, Shamshirsaz AA, Mustafa HJ, Sun RC, Espinoza J, Nassr AA, Sanz-Cortes M, Ugoji CH, Harman C, Turan O, Belfort MA, Donepudi R. Impact of middle cerebral artery pulsatility index on donor survival in twin-twin transfusion syndrome. Prenat Diagn. 2023 Jan;43(1):102-108. doi: 10.1002/pd.6288. Epub 2022 Dec 27. PubMed PMID: 36539914.
 
Mustafa HJ, Javinani A, Krispin E, Tadbiri H, Espinoza J, Shamshirsaz AA, Nassr AA, Donepudi R, Belfort MA, Cortes MS, Harman C, Turan OM. Fetoscopic laser surgery for twin-to-twin transfusion syndrome in DCTA triplets compared to MCDA twins: collaborative study and literature review. J Matern Fetal Neonatal Med. 2022 Dec;35(26):10348-10354. doi: 10.1080/14767058.2022.2128649. Epub 2022 Dec 18. Review. PubMed PMID: 36529927.
 
Nassr AA, Gessner M, Mostafaei S, Hessami K, Espinoza J, Donepudi RV, Sanz Cortes M, Krispin E, Sun RC, Qaderi S, Turan OM, Mustafa HJ, Harman C, Belfort MA, Shamshirsaz AA. Perinatal outcomes of twin-to-twin transfusion syndrome associated with evidence of twin anemia polycythemia using different standardized definitions. Eur J Obstet Gynecol Reprod Biol. 2022 Dec;279:45-49. doi: 10.1016/j.ejogrb.2022.10.007. Epub 2022 Oct 12. PubMed PMID: 36244240.
 
Mustafa HJ, Seif K, Javinani A, Aghajani F, Orlinsky R, Alvarez MV, Ryan A, Crimmins S. Gestational weight gain below instead of within the guidelines per class of maternal obesity: a systematic review and meta-analysis of obstetrical and neonatal outcomes. Am J Obstet Gynecol MFM. 2022 Sep;4(5):100682. doi: 10.1016/j.ajogmf.2022.100682. Epub 2022 Jun 18. Review. PubMed PMID: 35728780.
 
Mustafa HJ, Goetzinger K, Turan OM. Single fetal demise following fetoscopic ablation for twin-to-twin transfusion syndrome-cohort study, systematic review, and meta-analysis: a response. Am J Obstet Gynecol. 2022 Sep;227(3):550-551. doi: 10.1016/j.ajog.2022.04.007. Epub 2022 Apr 13. PubMed PMID: 35427538.
 
Mustafa HJ, Cermak R, Pedersen N, Harman C, Turan OM. Perinatal outcomes of pregnancies with twin-anemia polycythemia sequence complicating twin-to-twin transfusion syndrome using different twin-anemia polycythemia sequence diagnostic criteria. Prenat Diagn. 2022 Jul;42(8):985-993. doi: 10.1002/pd.6195. Epub 2022 Jun 28. PubMed PMID: 35686505.
 
Mustafa HJ, Javinani A, Krispin E, Tadbiri H, Shamshirsaz AA, Espinoza J, Nassr AA, Donepudi R, Belfort MA, Sanz Cortes M, Harman C, Turan OM. Perinatal outcomes of fetoscopic laser surgery for twin-twin transfusion syndrome in triplet pregnancy: cohort study, systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2022 Jul;60(1):42-51. doi: 10.1002/uog.24887. Review. PubMed PMID: 35229918.
 
Mustafa HJ, Javinani A, Goetzinger K, Aghajani F, Harman C, Shamshirsaz AA, Sanz Cortes M, Donepudi RV, Krispin E, Nassr AA, Espinoza J, Belfort MA, Turan OM. Single fetal demise following fetoscopic ablation for twin-to-twin transfusion syndrome-cohort study, systematic review, and meta-analysis. Am J Obstet Gynecol. 2022 Jun;226(6):843.e1-843.e28. doi: 10.1016/j.ajog.2022.02.035. Epub 2022 Mar 4. PubMed PMID: 35257668.
 
Mustafa HJ, Tadbiri H, Pedersen N, Harman C, Turan OM. Proximate Cord Insertion in Twin-to-Twin Transfusion Syndrome: Case Series and PRISMA Compliant Systematic Review and Meta-Analysis. Fetal Diagn Ther.2022;49(4):180-189. doi: 10.1159/000524162. Epub 2022 Apr 4. PubMed PMID: 35378537.
 
Krispin E, Mustafa HJ, Sun RC, Donepudi R, Espinoza J, Nassr AA, Belfort MA, Sanz Cortes M, Mostafaei S, Harman C, Turan O, Shamshirsaz AA. Iatrogenic chorioamniotic separation and septostomy following fetoscopic laser photocoagulation for twin-twin transfusion syndrome. Ultrasound Obstet Gynecol. 2022 Apr;59(4):506-512. doi: 10.1002/uog.23723. Epub 2022 Mar 10. PubMed PMID: 34182599.
 
Mustafa HJ, Krispin E, Tadbiri H, Espinoza J, Shamshirsaz AA, Nassr AA, Donepudi R, Belfort MA, Cortes MS, Pederson N, Harman C, Turan OM. Efficacy of long-term indomethacin therapy in prolonging pregnancy after fetoscopic laser surgery for twin-to-twin transfusion syndrome: a collaborative cohort study. BJOG. 2022 Mar;129(4):597-606. doi: 10.1111/1471-0528.17017. Epub 2021 Dec 1. PubMed PMID: 34780110.
 
Donepudi R, Krispin E, Mustafa H, Espinoza J, Nassr AA, Belfort MA, Sanz Cortes M, Mostafaei S, Harman C, Turan O, Shamshirsaz AA. Twin twin transfusion syndrome with and without selective fetal growth restriction: Predictors of donor demise. Prenat Diagn. 2021 Nov;41(12):1524-1530. doi: 10.1002/pd.6049. Epub 2021 Oct 17. PubMed PMID: 34570378.
 
Mustafa HJ, Tessier KM, Reagan LA, Luo X, Contag SA. Fetal growth standards for Somali population. J Matern Fetal Neonatal Med. 2021 Aug;34(15):2440-2453. doi: 10.1080/14767058.2019.1667327. Epub 2019 Sep 23. PubMed PMID: 31544565; PubMed Central PMCID: PMC7085970.
 
Lahrouchi N, Postma AV, Salazar CM, De Laughter DM, Tjong F, Piherová L, Bowling FZ, Zimmerman D, Lodder EM, Ta-Shma A, Perles Z, Beekman L, Ilgun A, Gunst Q, Hababa M, Škoric-Milosavljevic D, Stránecký V, Tomek V, de Knijff P, de Leeuw R, Robinson JY, Burn SC, Mustafa H, Ambrose M, Moss T, Jacober J, Niyazov DM, Wolf B, Kim KH, Cherny S, Rousounides A, Aristidou-Kallika A, Tanteles G, Ange-Line B, Denommé-Pichon AS, Francannet C, Ortiz D, Haak MC, Ten Harkel AD, Manten GT, Dutman AC, Bouman K, Magliozzi M, Radio FC, Santen GW, Herkert JC, Brown HA, Elpeleg O, van den Hoff MJ, Mulder B, Airola MV, Kmoch S, Barnett JV, Clur SA, Frohman MA, Bezzina CR. Biallelic loss-of-function variants in PLD1 cause congenital right-sided cardiac valve defects and neonatal cardiomyopathy. J Clin Invest. 2021 Mar 1;131(5). doi: 10.1172/JCI142148. PubMed PMID: 33645542; PubMed Central PMCID: PMC7919725.
 
Putri DS, Berkebile ZW, Mustafa HJ, Fernández-Alarcón C, Abrahante JE, Schleiss MR, Bierle CJ. Cytomegalovirus infection elicits a conserved chemokine response from human and guinea pig amnion cells. Virology. 2020 Sep;548:93-100. doi: 10.1016/j.virol.2020.06.005. Epub 2020 Jun 17. PubMed PMID: 32838950; PubMed Central PMCID: PMC7447834.
 
Mustafa HJ, Wong HL, Al-Kofahi M, Schaefer M, Karanam A, Todd MM. Bupivacaine Pharmacokinetics and Breast Milk Excretion of Liposomal Bupivacaine Administered After Cesarean Birth. Obstet Gynecol. 2020 Jul;136(1):70-76. doi: 10.1097/AOG.0000000000003886. PubMed PMID: 32541292; PubMed Central PMCID: PMC7316148.
 
Mustafa HJ, Cross SN, Jacobs KM, Tessier KM, Tofte AN, McCarter AR, Narasimhan SL. Preterm Birth of Infants Prenatally Diagnosed with Congenital Heart Disease, Characteristics, Associations, and Outcomes. Pediatr Cardiol. 2020 Jun;41(5):972-978. doi: 10.1007/s00246-020-02345-8. Epub 2020 Apr 30. PubMed PMID: 32356015; PubMed Central PMCID: PMC7394484.
 
Mustafa HJ, Jacobs KM, Tessier KM, Narasimhan SL, Tofte AN, McCarter AR, Cross SN. Chromosomal microarray analysis in the investigation of prenatally diagnosed congenital heart disease. Am J Obstet Gynecol MFM. 2020 Feb;2(1):100078. doi: 10.1016/j.ajogmf.2019.100078. Epub 2019 Dec 27. PubMed PMID: 33345990.
 
 
 
 
 
 

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