Christie M. Orschell, PhD
Robert Wallace Miller Professor of Oncology
Professor of Medicine
Adjunct Professor of Anatomy, Cell Biology & Physiology
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Joseph E. Walther Hall, Room C341
980 W. Walnut St.
Indianapolis , IN 46202 - PubMed:
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| Year | Degree | Institution |
|---|---|---|
| 1994 | Postdoctoral Training | Indiana University, Indianapolis, IN |
| 1992 | PhD | Indiana University |
| 1986 | BS | Indiana University |
Acute and delayed effects of radiation exposure on the hematopoietic system and hematopoietic stem cell biology
Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding.
Dynlacht JR; Garrett J; Joel R; Lane K; Mendonca MS; Orschell CM; Radiation research 2017 Apr 24
Dynlacht JR; Garrett J; Joel R; Lane K; Mendonca MS; Orschell CM; Radiation research 2017 Apr 24
An oral Hemokine<sup>TM</sup>, a-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo.
Faller DV; Castaneda SA; Zhou D; Vedamony M; Newburger PE; White GL; Kosanke S; Plett PA; Orschell CM; Boosalis MS; Perrine SP; Blood cells, molecules & diseases 2016 Oct 31
Faller DV; Castaneda SA; Zhou D; Vedamony M; Newburger PE; White GL; Kosanke S; Plett PA; Orschell CM; Boosalis MS; Perrine SP; Blood cells, molecules & diseases 2016 Oct 31
Combined Hydration and Antibiotics with Lisinopril to Mitigate Acute and Delayed High-dose Radiation Injuries to Multiple Organs.
Fish BL; Gao F; Narayanan J; Bergom C; Jacobs ER; Cohen EP; Moulder JE; Orschell CM; Medhora M; Health physics 2016 Nov
Fish BL; Gao F; Narayanan J; Bergom C; Jacobs ER; Cohen EP; Moulder JE; Orschell CM; Medhora M; Health physics 2016 Nov
Delayed Effects of Acute Radiation Exposure in a Murine Model of the H-ARS: Multiple-Organ Injury Consequent to <10 Gy Total Body Irradiation.
Unthank JL; Miller SJ; Quickery AK; Ferguson EL; Wang M; Sampson CH; Chua HL; DiStasi MR; Feng H; Fisher A; Katz BP; Plett PA; Sandusky GE; Sellamuthu R; Vemula S; Cohen EP; MacVittie TJ; Orschell CM; Health physics 2015 Nov
Unthank JL; Miller SJ; Quickery AK; Ferguson EL; Wang M; Sampson CH; Chua HL; DiStasi MR; Feng H; Fisher A; Katz BP; Plett PA; Sandusky GE; Sellamuthu R; Vemula S; Cohen EP; MacVittie TJ; Orschell CM; Health physics 2015 Nov
The H-ARS Dose Response Relationship (DRR): Validation and Variables.
Plett PA; Sampson CH; Chua HL; Jackson W; Vemula S; Sellamuthu R; Fisher A; Feng H; Wu T; MacVittie TJ; Orschell CM; Health physics 2015 Nov
Plett PA; Sampson CH; Chua HL; Jackson W; Vemula S; Sellamuthu R; Fisher A; Feng H; Wu T; MacVittie TJ; Orschell CM; Health physics 2015 Nov
Relationships Between Renal Parameters and Serum and Urine Markers of Inflammation in Those With and Without HIV Infection.
Shinha T; Mi D; Liu Z; Orschell CM; Lederman MM; Gupta SK; AIDS research and human retroviruses 2015 Feb 26
Shinha T; Mi D; Liu Z; Orschell CM; Lederman MM; Gupta SK; AIDS research and human retroviruses 2015 Feb 26
Subcutaneous wounding postirradiation reduces radiation lethality in mice.
Garrett J; Orschell CM; Mendonca MS; Bigsby RM; Dynlacht JR; Radiation research 2014 May 8
Garrett J; Orschell CM; Mendonca MS; Bigsby RM; Dynlacht JR; Radiation research 2014 May 8
Prognostic biomarkers for acute graft-versus-host disease risk after cyclophosphamide-fludarabine nonmyeloablative allotransplantation.
Nelson RP Jr; Khawaja MR; Perkins SM; Elmore L; Mumaw CL; Orschell C; Paczesny S; Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2014 Jul 10
Nelson RP Jr; Khawaja MR; Perkins SM; Elmore L; Mumaw CL; Orschell C; Paczesny S; Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2014 Jul 10
Survival efficacy of the PEGylated G-CSFs Maxy-G34 and neulasta in a mouse model of lethal H-ARS, and residual bone marrow damage in treated survivors.
Chua HL; Plett PA; Sampson CH; Katz BP; Carnathan GW; MacVittie TJ; Lenden K; Orschell CM; Health physics 2014 Jan
Chua HL; Plett PA; Sampson CH; Katz BP; Carnathan GW; MacVittie TJ; Lenden K; Orschell CM; Health physics 2014 Jan
PEGylated G-CSF (BBT-015), GM-CSF (BBT-007), and IL-11 (BBT-059) analogs enhance survival and hematopoietic cell recovery in a mouse model of the hematopoietic syndrome of the acute radiation syndrome.
Plett PA; Chua HL; Sampson CH; Katz BP; Fam CM; Anderson LJ; Cox GN; Orschell CM; Health physics 2014 Jan
Plett PA; Chua HL; Sampson CH; Katz BP; Fam CM; Anderson LJ; Cox GN; Orschell CM; Health physics 2014 Jan
Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation.
Cheng YH; Hooker RA; Nguyen K; Gerard-O'Riley R; Waning DL; Chitteti BR; Meijome TE; Chua HL; Plett AP; Orschell CM; Srour EF; Mayo LD; Pavalko FM; Bruzzaniti A; Kacena MA; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Jun
Cheng YH; Hooker RA; Nguyen K; Gerard-O'Riley R; Waning DL; Chitteti BR; Meijome TE; Chua HL; Plett AP; Orschell CM; Srour EF; Mayo LD; Pavalko FM; Bruzzaniti A; Kacena MA; Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013 Jun
Long-term hematopoietic stem cell damage in a murine model of the hematopoietic syndrome of the acute radiation syndrome.
Chua HL; Plett PA; Sampson CH; Joshi M; Tabbey R; Katz BP; MacVittie TJ; Orschell CM; Health physics 2012 Oct
Chua HL; Plett PA; Sampson CH; Joshi M; Tabbey R; Katz BP; MacVittie TJ; Orschell CM; Health physics 2012 Oct
Establishing a murine model of the hematopoietic syndrome of the acute radiation syndrome.
Plett PA; Sampson CH; Chua HL; Joshi M; Booth C; Gough A; Johnson CS; Katz BP; Farese AM; Parker J; MacVittie TJ; Orschell CM; Health physics 2012 Oct
Plett PA; Sampson CH; Chua HL; Joshi M; Booth C; Gough A; Johnson CS; Katz BP; Farese AM; Parker J; MacVittie TJ; Orschell CM; Health physics 2012 Oct
Recovery from hematopoietic injury by modulating prostaglandin E(2) signaling post-irradiation.
Hoggatt J; Singh P; Stilger KN; Plett PA; Sampson CH; Chua HL; Orschell CM; Pelus LM; Blood cells, molecules & diseases 2012 Nov 30
Hoggatt J; Singh P; Stilger KN; Plett PA; Sampson CH; Chua HL; Orschell CM; Pelus LM; Blood cells, molecules & diseases 2012 Nov 30
Thrice weekly azacitidine does not improve hematological responses in lower-risk myelodysplastic syndromes: a study of the Hoosier Oncology Group.
Sayar H; Chan RJ; Orschell CM; Chan EM; Yu Z; Hood D; Plett A; Yang Z; Hui CL; Nabinger SC; Kohlbacher KJ; West ES; Walter A; Sampson C; Wu J; Cripe LD; Leukemia research 2011 Mar 21
Sayar H; Chan RJ; Orschell CM; Chan EM; Yu Z; Hood D; Plett A; Yang Z; Hui CL; Nabinger SC; Kohlbacher KJ; West ES; Walter A; Sampson C; Wu J; Cripe LD; Leukemia research 2011 Mar 21
Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells.
Orschell CM; Borneo J; Munugalavadla V; Ma P; Sims E; Ramdas B; Yoder MC; Kapur R; Experimental hematology 2008 Mar 17
Orschell CM; Borneo J; Munugalavadla V; Ma P; Sims E; Ramdas B; Yoder MC; Kapur R; Experimental hematology 2008 Mar 17
Src family kinase-mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors.
Borneo J; Munugalavadla V; Sims EC; Vemula S; Orschell CM; Yoder M; Kapur R; Experimental hematology 2007 Jul
Borneo J; Munugalavadla V; Sims EC; Vemula S; Orschell CM; Yoder M; Kapur R; Experimental hematology 2007 Jul
Shp-2 heterozygous hematopoietic stem cells have deficient repopulating ability due to diminished self-renewal.
Chan RJ; Li Y; Hass MN; Walter A; Voorhorst CS; Shelley WC; Yang Z; Orschell CM; Yoder MC; Experimental hematology 2006 Sep
Chan RJ; Li Y; Hass MN; Walter A; Voorhorst CS; Shelley WC; Yang Z; Orschell CM; Yoder MC; Experimental hematology 2006 Sep
Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer.
Srirangam A; Mitra R; Wang M; Gorski JC; Badve S; Baldridge L; Hamilton J; Kishimoto H; Hawes J; Li L; Orschell CM; Srour EF; Blum JS; Donner D; Sledge GW; Nakshatri H; Potter DA; Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Mar 15
Srirangam A; Mitra R; Wang M; Gorski JC; Badve S; Baldridge L; Hamilton J; Kishimoto H; Hawes J; Li L; Orschell CM; Srour EF; Blum JS; Donner D; Sledge GW; Nakshatri H; Potter DA; Clinical cancer research : an official journal of the American Association for Cancer Research 2006 Mar 15
Endothelial-monocyte-activating polypeptide II induces migration of endothelial progenitor cells via the chemokine receptor CXCR3.
Hou Y; Plett PA; Ingram DA; Rajashekhar G; Orschell CM; Yoder MC; March KL; Clauss M; Experimental hematology 2006 Aug
Hou Y; Plett PA; Ingram DA; Rajashekhar G; Orschell CM; Yoder MC; March KL; Clauss M; Experimental hematology 2006 Aug
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist.
Broxmeyer HE; Orschell CM; Clapp DW; Hangoc G; Cooper S; Plett PA; Liles WC; Li X; Graham-Evans B; Campbell TB; Calandra G; Bridger G; Dale DC; Srour EF; The Journal of experimental medicine 2005 Apr 18
Broxmeyer HE; Orschell CM; Clapp DW; Hangoc G; Cooper S; Plett PA; Liles WC; Li X; Graham-Evans B; Campbell TB; Calandra G; Bridger G; Dale DC; Srour EF; The Journal of experimental medicine 2005 Apr 18
A role for the Fanconi anemia C protein in maintaining the DNA damage-induced G2 checkpoint.
Freie BW; Ciccone SL; Li X; Plett PA; Orschell CM; Srour EF; Hanenberg H; Schindler D; Lee SH; Clapp DW; The Journal of biological chemistry 2004 Sep 17
Freie BW; Ciccone SL; Li X; Plett PA; Orschell CM; Srour EF; Hanenberg H; Schindler D; Lee SH; Clapp DW; The Journal of biological chemistry 2004 Sep 17
Modulation of in vitro proliferation kinetics and primitive hematopoietic potential of individual human CD34+CD38-/lo cells in G0.
Srour EF; Tong X; Sung KW; Plett PA; Rice S; Daggy J; Yiannoutsos CT; Abonour R; Orschell CM; Blood 2004 Dec 21
Srour EF; Tong X; Sung KW; Plett PA; Rice S; Daggy J; Yiannoutsos CT; Abonour R; Orschell CM; Blood 2004 Dec 21
Impact of modeled microgravity on migration, differentiation, and cell cycle control of primitive human hematopoietic progenitor cells.
Plett PA; Abonour R; Frankovitz SM; Orschell CM; Experimental hematology 2004 Aug
Plett PA; Abonour R; Frankovitz SM; Orschell CM; Experimental hematology 2004 Aug
Distribution of marrow repopulating cells between bone marrow and spleen early after transplantation.
Plett PA; Frankovitz SM; Orschell CM; Blood 2003 May 29
Plett PA; Frankovitz SM; Orschell CM; Blood 2003 May 29
Fanconi anemia type C-deficient hematopoietic stem/progenitor cells exhibit aberrant cell cycle control.
Li X; Plett PA; Yang Y; Hong P; Freie B; Srour EF; Orschell CM; Clapp DW; Haneline LS; Blood 2003 May 22
Li X; Plett PA; Yang Y; Hong P; Freie B; Srour EF; Orschell CM; Clapp DW; Haneline LS; Blood 2003 May 22
Peripheral blood "endothelial progenitor cells" are derived from monocyte/macrophages and secrete angiogenic growth factors.
Rehman J; Li J; Orschell CM; March KL; Circulation 2003 Mar 4
Rehman J; Li J; Orschell CM; March KL; Circulation 2003 Mar 4
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