26044-Hockerman, Gregory

Gregory H. Hockerman, PhD

Adjunct Professor of Pharmacology & Toxicology

Phone
(765) 496-3874
Address
Purdue University
RHPH 206A
West Lafayette, IN 47907
PubMed:

Bio

Dr. Gregory Hockerman is the Associate Head and Professor of Medicinal Chemistry and Molecular Pharmacology at Purdue University specializing in molecular pharmacology. He also serves as the Pharmacology Discipline Leader at IUSM-WL.

1991-1997: Postdoctoral Fellow, Pharmacology, University of Washington

1997-1998: Research Assistant Professor, Pharmacology, University of Washington

1998-2004: Assistant Professor of Medicinal Chemistry and Molecular Pharmacology, Purdue University College of Pharmacy

2004-2014: Associate Professor of Medicinal Chemistry and Molecular Pharmacology, Purdue University College of Pharmacy

2014-present: Professor of Medicinal Chemistry and Molecular Pharmacology, Purdue University College of Pharmacy

2014-present: Adjunct Professor of Pharmacology and Toxicology, Indiana University School of Medicine

Key Publications

Hockerman, G.H., Pratt, E.P.S., Guha, S., LaVigne, E.K., Whitmore, C., Khader, O., McClure, N., Zampieri, S., Koran, J., Wang, W-H., and Pond, A.L. ERG1a K+ channel increases intracellular calcium concentration through modulation of calsequestrin1 in C2C12 myotubes.  Sci Rep 15:9480 (2025). Doi: 10.1038/s41598-025-93788-

 Harvey, K.E., Tang, S., LaVigne, E.K., Pratt, E.S.P., and Hockerman, G.H.  RyR2 regulates store operated Ca2+ entry, phospholipase C activity, and electrical excitability in the insulinoma cell line INS-1.  PLoS ONE 18(5): e0285316 (2023). doi: 10.1371/journal.pone.0285316

 Harvey, K.E., LaVigne, E.K., Saleem, M.D., Salyer, A.E., Pratt, E.S.P., Sample, P.A., Gowher, H., and Hockerman, G.H.  RYR2/IRBIT regulates insulin gene transcript, insulin content, and secretion in the insulinoma cell line INS-1. Sci Rep 12:7713 (2022).  doi: 10.1038/s41598-022-11276-8

 Pratt, E.P.S, Salyer, A.E., Harvey, K.E., Hockerman, G.H.  Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic beta cells.  PLoS ONE 14(8):e0215188 (2019)

 Wang, Y., Tang, S., Harvey, K.E., Salyer, A.E., Li, T., Rantz, E.K., Lill, M.A., and Hockerman, G.H. Molecular determinants of the differential modulation of Cav1.2 and Cav1.3 by nifedipine and FPL 64176. Mol Pharmacol 94:973-983 (2018)

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