26044-Hockerman, Gregory

Gregory H. Hockerman, PhD

Adjunct Professor of Pharmacology & Toxicology

Phone
(765) 496-3874
Address
Purdue University
RHPH 206A
West Lafayette, IN 47907
PubMed:

Bio

1991-1997                      Postdoctoral Fellow, Pharmacology, University of Washington

 1997-1998                     Research Assistant Professor, Pharmacology, University of Washington

  1998-2004                    Assistant Professor of Medicinal Chemistry and Molecular Pharmacology,

                                         Purdue University College of Pharmacy

   2004-2014                   Associate Professor of Medicinal Chemistry and Molecular Pharmacology

                                           Purdue University College of Pharmacy

    2014-present             Professor of Medicinal Chemistry and Molecular Pharmacology

                                           Purdue University College of Pharmacy

    2014-present             Adjunct Professor of Pharmacology and Toxicology

                                           Indiana University School of Medicine

Key Publications

Hockerman, G.H., Pratt, E.P.S., Guha, S., LaVigne, E.K., Whitmore, C., Khader, O., McClure, N., Zampieri, S., Koran, J., Wang, W-H., and Pond, A.L. ERG1a K+ channel increases intracellular calcium concentration through modulation of calsequestrin1 in C2C12 myotubes.  Sci Rep 15:9480 (2025). Doi: 10.1038/s41598-025-93788-

 Harvey, K.E., Tang, S., LaVigne, E.K., Pratt, E.S.P., and Hockerman, G.H.  RyR2 regulates store operated Ca2+ entry, phospholipase C activity, and electrical excitability in the insulinoma cell line INS-1.  PLoS ONE 18(5): e0285316 (2023). doi: 10.1371/journal.pone.0285316

 Harvey, K.E., LaVigne, E.K., Saleem, M.D., Salyer, A.E., Pratt, E.S.P., Sample, P.A., Gowher, H., and Hockerman, G.H.  RYR2/IRBIT regulates insulin gene transcript, insulin content, and secretion in the insulinoma cell line INS-1. Sci Rep 12:7713 (2022).  doi: 10.1038/s41598-022-11276-8

 Pratt, E.P.S, Salyer, A.E., Harvey, K.E., Hockerman, G.H.  Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic beta cells.  PLoS ONE 14(8):e0215188 (2019)

 Wang, Y., Tang, S., Harvey, K.E., Salyer, A.E., Li, T., Rantz, E.K., Lill, M.A., and Hockerman, G.H. Molecular determinants of the differential modulation of Cav1.2 and Cav1.3 by nifedipine and FPL 64176. Mol Pharmacol 94:973-983 (2018)

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