21384-Ceppa, Eugene

Eugene P. Ceppa, MD

Professor of Surgery

Section Chief of HPB Surgery

Associate Division Chief of Surgical Oncology

Director of IU Hereditary Pancreatic Cancer Screening

Email
eceppa@iu.edu
Phone
317-944-5013
Address
EH 500
SONC
IN
Indianapolis, IN
PubMed:

Bio

Dr. Ceppa is a Professor of Surgery with tenure at the IU School of Medicine.  He completed his undergraduate degree in Biophysics/Near East Asian Studies and medical doctorate at the Johns Hopkins University (1995-2003). He went to the Duke University Medical Center to complete his general surgery residency (2003-2010) with a two-year research fellowship at UCSF (2005-2007) studying mechanisms of pain signaling in pancreatitis. He completed two advanced surgical fellowships in minimally invasive/bariatric surgery at Duke University (2011) accredited by the Fellowship Council/ASMBS and hepatopancreatobiliary (HPB) surgery at Indiana University (2012) accredited by the Fellowship Council/AHPBA.  Received his certification in general surgery by the American Board of Surgery in 2011.

Since joining the faculty at the IU School of Medicine in 2012, he has developed a surgical practice focused on minimally invasive gastrointestinal surgery with a focus in benign & malignant disease of the liver, pancreas, gallbladder, and biliary system, as well as benign foregut disease and abdominal wall hernia. His minimally invasive practice includes laparoscopic, endoscopic, and robotic surgery. His research interests include hereditary pancreatic cancer as well as minimally invasive HPB surgery. 

He previously held numerous educational roles as the associate program director of the IU general surgery residency and IU HPB surgery fellowship. Currently, serves as the section Chief of HPB Surgery, associate division Chief of Surgical Oncology and the Director of the Hereditary Pancreatic Cancer Program at the IU School of Medicine.   Additional scholarly roles include serving as the senior editor to the SAGES Evolving Techniques in Pancreatic Surgery and as the subject editor of hepatopancreatobiliary disease for the journal Surgical Endoscopy. His research interests are similar to his clinical interests which have resulted in over 150 peer-reviewed publications, 30 book-chapters, and 200 abstracts for presentation at national and international meetings.  Serves as the principal investigator for multiple externally funded grants for active clinical trials.

Educational Timeline:

Johns Hopkins University - Undergraduate (1995-1999)

Johns Hopkins University - School of Medicine (1999-2003)

Duke University - General Surgery Residency (2003-2005)

University of California, San Francisco - Surgical Research Fellowship (2005-2007)

Duke University - General Surgery Residency (2007-2010)

Duke University - Minimally Invasive/Bariatric Surgery Fellowship (2010-2011)

Indiana University - Hepatopancreatobiliary Surgery Fellowship (2011-2012)

Key Publications

 

Enucleation for insulinoma: consolidating evidence through systematic review and meta-analysis.
Alogakos M, Nakanishi H, Athanasiadis DI, Farsi S, Shreehari Suresh, Witkowiak MM, Abdulsalam FAM, Than CA, McKenzie TJ, Ceppa EP.Surg Endosc. 2025 Oct;39(10):6352-6365. doi: 10.1007/s00464-025-12099-0. Epub 2025 Sep 2.PMID: 40897878
 
 
SAGES/AHPBA guidelines for the use of microwave and radiofrequency liver ablation for the surgical treatment of hepatocellular carcinoma or colorectal liver metastases less than 5 cm.
Ceppa EP, Collings AT, Abdalla M, Onkendi E, Nelson DW, Ozair A, Miraflor E, Rahman F, Whiteside J, Shah MM, Ayloo S, Dirks R, Kumar SS, Ansari MT, Sucandy I, Ali K, Douglas S, Polanco PM, Vreeland TJ, Buell J, Abou-Setta AM, Awad Z, Kwon CH, Martinie JB, Sbrana F, Pryor A, Slater BJ, Richardson W, Jeyarajah R, Alseidi A.Surg Endosc. 2023 Dec;37(12):8991-9000. doi: 10.1007/s00464-023-10468-1. Epub 2023 Nov 13.PMID: 37957297
 
Patients with deleterious germline mutations: A heterogeneous population for pancreatic cancer screening?
Roch AM, Kim RC, Nguyen TK, House MG, Zyromski NJ, Nakeeb A, Schmidt CM, Ceppa EP.J Surg Oncol. 2023 Aug;128(2):289-294. doi: 10.1002/jso.27289. Epub 2023 Apr 21.PMID: 37083062
 
Surgical approach to microwave and radiofrequency liver ablation for hepatocellular carcinoma and colorectal liver metastases less than 5 cm: a systematic review and meta-analysis.
Abdalla M, Collings AT, Dirks R, Onkendi E, Nelson D, Ozair A, Miraflor E, Rahman F, Whiteside J, Shah MM, Ayloo S, Abou-Setta A, Sucandy I, Kchaou A, Douglas S, Polanco P, Vreeland T, Buell J, Ansari MT, Pryor AD, Slater BJ, Awad Z, Richardson W, Alseidi A, Jeyarajah DR, Ceppa E.Surg Endosc. 2023 May;37(5):3340-3353. doi: 10.1007/s00464-022-09815-5. Epub 2022 Dec 21.PMID: 36542137
 
Closed Incision Negative Pressure Therapy to Reduce Surgical Site Infection in High-Risk Gastrointestinal Surgery: A Randomized Controlled Trial.
Ceppa EP, Kim RC, Niedzwiecki D, Lowe ME, Warren DA, House MG, Nakeeb A, Zani S, Moyer AN, Blazer DG 3rd; Closed Incision Negative Pressure Therapy (ciNPT) Investigators.J Am Coll Surg. 2023 Apr 1;236(4):698-708. doi: 10.1097/XCS.0000000000000547. Epub 2023 Jan 10.PMID: 36728375 Clinical Trial.
 
Are BRCA1 and BRCA2 gene mutation patients underscreened for pancreatic adenocarcinoma?
Roch AM, Schneider J, Carr RA, Lancaster WP, House MG, Zyromski NJ, Nakeeb A, Schmidt CM, Ceppa EP.J Surg Oncol. 2019 May;119(6):777-783. doi: 10.1002/jso.25376. Epub 2019 Jan 12.PMID: 30636051
 
Laparoscopic distal pancreatectomy for pancreatic cancer is safe and effective.  Bauman MD, Becerra DG, Kilbane EM, Zyromski NJ, Schmidt CM, Pitt HA, Nakeeb A, House MG, Ceppa EP.Surg Endosc. 2018 Jan;32(1):53-61. doi: 10.1007/s00464-017-5633-7. Epub 2017 Jun 22.PMID: 28643065
 

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