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Faculty Research Labs

Dage Lab

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The laboratory of Jeffrey L. Dage, PhD, is focused on the discovery and development of biomarkers to aid in the understanding of neurodegenerative diseases. Dr. Dage has more than 20 years of experience in drug discovery and early clinical development holding roles as an individual contributor, scientific group leader and management. He has successfully led research groups in diverse areas such as analytical chemistry, stem cell biology and translational science with broad impact across therapeutic areas. 

Female researcher pipetting in a labDr. Dage has continually been on the forefront of identification, development, and application of novel technologies that answer disease relevant biological questions encountered in the course of drug discovery and clinical development. Most recently he has led the discovery and development of phosphorylated tau as a novel blood biomarker for Alzheimer’s disease clinical trials. This blood test has proven to be useful for identification of Alzheimer’s disease pathology and risk of cognitive decline.

Dr. Dage is also the Scientific Director for the Biomarker Assay Laboratory in the National Centralized Repository for Alzheimer’s Disease and Related Dementias (NCRAD).

IN THE NEWS

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Indiana has pioneered the discovery and development of blood tests for Alzheimer’s disease, specifically P-tau217, revolutionizing the diagnosis and treatment of the disease worldwide. Donors now have a unique opportunity to collaborate with researchers at the Indiana University School of Medicine, contributing to the advancement of new tests that pave the way for precision medicine.
publications
research team
Jeffrey Dage lab
faculty investigators
Principal Investigator
60676-Dage, Jeff

Jeff Dage, PhD

Senior Research Professor of Neurology

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42900-Russ, Kristen

Kristen A. Russ, PhD

NCRAD Biomarker Assay Lab Director

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62996-Khan, Naazneen

Naazneen Khan, PhD

Assistant Research Professor of Neurology

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Postdoctoral fellows
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Jennifer A. Hensel, PhD

Postdoctoral Fellow in Neurology

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lab staff
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Zijin Zhao, MS

Research Analyst

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Xiaoping Gu, MS

Research Analyst

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Lily Roskam, BS

Research Analyst

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Mara Stecker, MS

Project Manager

Clinical staff
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Ralitsa Kostadinova, BA

Clinical Research Specialist

graduate students
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John Hoffman

MedNeuro PhD Student

past lab members

Audrey Lee-Gosselin, MS - Senior Scientist at Eli Lilly and Company

Sri Kanuri, PhD 

Interns

Jessica Bray (Summer 2024)

Nikhail (Summer 2023-24)

Mia Fleisher-De Kozan (Summer 2022)

Sophie Phoenix (Summer 2022)